Title: Metal oxide nano-composite magnetic material, fabrication method, and method for linkage, enrichment, and isolation of phosphorylated species
Authors: Chen Yu-Chie
Chen Cheng-Tai
Chen Wei-Yu
Lo Chun-Yuen
Lin Hong-Yi
Liu Chih-Chi
Issue Date: 27-May-2014
Abstract: The present invention relates to a metal oxide nano-composite magnetic material, fabrication method, and method for linkage, enrichment, and isolation of phosphorylated species. The metal oxide nano-composite magnetic material comprises the magnetic iron oxide nanoparticle, a silica layer immobilized onto the magnetic iron oxide nanoparticle and a metal oxide layer coated onto the silica layer. The magnetic iron oxide nanoparticles can be used for absorbing microwave radiation to accelerate the enrichment and linkage for phosphorylated species onto the metal oxide nano-composite magnetic material. Furthermore, the magnetic property of magnetic iron oxide nanoparticles leads to isolation of the metal oxide nano-composite magnetic material-target species conjugates by simply employing an external magnetic field. The specificity of the metal oxide on the surface of the metal oxide nano-composite magnetic material for phosphorylated species also leads to the linkage/enrichment of phosphorylated species with high selectivity.
Gov't Doc #: G01N033/552
G01N033/551
URI: http://hdl.handle.net/11536/104377
Patent Country: USA
Patent Number: 08735176
Appears in Collections:Patents


Files in This Item:

  1. 08735176.pdf

If it is a zip file, please download the file and unzip it, then open index.html in a browser to view the full text content.