A "turn on/off" scorpion biosensor targeting point mutation of SMN genes for diagnosis of spinal muscular atrophy

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DC Field	Value	Language
dc.contributor.author	Chen, Chung-An	en_US
dc.contributor.author	Wang, Chun-Chi	en_US
dc.contributor.author	Chen, Yen-Ling	en_US
dc.contributor.author	Jong, Yuh-Jyh	en_US
dc.contributor.author	Wu, Shou-Mei	en_US
dc.date.accessioned	2014-12-08T15:36:14Z	-
dc.date.available	2014-12-08T15:36:14Z	-
dc.date.issued	2014	en_US
dc.identifier.issn	1359-7345	en_US
dc.identifier.uri	http://hdl.handle.net/11536/24568	-
dc.identifier.uri	http://dx.doi.org/10.1039/c4cc03472d	en_US
dc.description.abstract	A "turn on/off\'\' biosensor for diagnosis of exon 7 of the SMN1 gene was developed by employing a "scorpion primer\'\'. This scorpion primer was based on the principle of fluorescence resonance energy transfer using a fluorophore, a blocker and a quencher. It was successfully applied to detect 10 volunteer samples, and not only to in vitro testing.	en_US
dc.language.iso	en_US	en_US
dc.title	A "turn on/off" scorpion biosensor targeting point mutation of SMN genes for diagnosis of spinal muscular atrophy	en_US
dc.type	Article	en_US
dc.identifier.doi	10.1039/c4cc03472d	en_US
dc.identifier.journal	CHEMICAL COMMUNICATIONS	en_US
dc.citation.volume	50	en_US
dc.citation.issue	59	en_US
dc.citation.spage	8069	en_US
dc.citation.epage	8072	en_US
dc.contributor.department	生物科技學院	zh_TW
dc.contributor.department	College of Biological Science and Technology	en_US
dc.identifier.wosnumber	WOS:000338439700039	-
dc.citation.woscount	1	-
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